CUAS: A DATABASE OF ANNOTATED TRANSCRIPTS GENERATED BY ALTERNATIVE SPLICING IN CUCUMBERS

CuAS: a database of annotated transcripts generated by alternative splicing in cucumbers

CuAS: a database of annotated transcripts generated by alternative splicing in cucumbers

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Abstract Background Alternative splicing (AS) plays a critical regulatory role in modulating transcriptome and proteome diversity.In particular, it increases the functional diversity of gruvi golden lager proteins.Recent genome-wide analysis of AS using RNA-Seq has revealed that AS is highly pervasive in plants.Furthermore, it has been suggested that most AS events are subject to tissue-specific regulation.

Description To reveal the functional characteristics induced by AS and tissue-specific splicing events, a database for exploring these characteristics is needed, especially in plants.To address these goals, we constructed a database of annotated transcripts generated by alternative splicing in cucumbers (CuAS: http://cmb.bnu.edu.

cn/alt_iso/index.php ) that integrates genomic annotations, isoform-level functions, isoform-level features, and tissue-specific AS events among multiple tissues.CuAS supports a retrieval system that identifies unique IDs (gene ID, isoform ID, UniProt ID, and gene name), chromosomal positions, and gene families, and a browser for visualization of each gene.Conclusion We believe that CuAS could be helpful 2000 bmw 528i front bumper for revealing the novel functional characteristics induced by AS and tissue-specific AS events in cucumbers.

CuAS is freely available at http://cmb.bnu.edu.cn/alt_iso/index.

php.

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